Guardion™: Precise Cryopreservation for Consistent, Scalable Results

An LN₂-free, cryopreservation system engineered for precision, speed and ease of use, from the lab, through to commercialisation.

The Benefits That Matter Most

Next-generation capabilities built to achieve faster, more reliable, and consistently uniform cryopreservation. Our integrated design minimizes variability, strengthens workflow control, and supports repeatable results across diverse samples, teams, and operational environments.
Seamless Integration

Rapid LN₂-Free Cryo

Ultra-fast freezing without LN₂ to cut cost and simplify operations.

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Precision Freezing

Engineered for precise, flexible freezing that matches your product’s needs.

Scalable Platform

Throughput + Flexibility

Supports fast batch processing with a portable, flexible design.

Future-Proof Expansion

Engineered for Reliability

Designed for consistent, robust performance in any setting.

Design That Delivers Superior
Freezing Performance

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Meet Guardion
1. Included Racks
Load bags or vials into the supplied racks – contactless options available.
2. Integrated Touchscreen
Access controls and LifeChain™-generated freeze curves through a clean, intuitive interface.
3. Casters for Mobility
Shift between stationary and mobile use with ease—LN₂-free operation lets you deploy anywhere.
4. Automated Sample Loading
The integrated manifold raises and lowers samples automatically with precise, controlled motion.
5. 30L Tank Capacity

Capacity to process a large number of samples in a single run to increase throughput and operational efficiency.

6. Cascade Refrigeration
Achieve ultra-fast cooling speeds without liquid nitrogen using our high-efficiency cascade system and pumps.
Heat-Maps

Designed for Precision

Traditional freeze methods (left vial), where surface-driven cooling creates a damaging igloo effect, is compared with Vitrafy’s intelligent approach (right vial). LifeChainTM algorithms set material-specific conditions and direct GuardionTM’s heat-transfer performance, enabling controlled, even cooling through the entire sample and preventing structural and cellular damage.

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Cryopreservation as Good as Fresh

Guardion™ rapidly freezes T-cells in under four minutes while maintaining post-thaw quality rivaling fresh controls. Viability remains exceptionally high—95% fresh vs. 94%, 93%, and 93% at 24, 48, and 72 hours (respectively) post thaw—demonstrating the effectiveness of our hardware-driven thermal precision in minimizing cellular stress and preserving functional integrity for critical cell types used in cell and gene therapy.

Built for Precision. Powered by Intelligence.

Innovation

Designed for Precision

Ultra-fast, adaptive freezing lets Guardion tailor curves to any study—material, packaging, or media—ensuring uniformity unmatched by vapor-based CRFs.

Data

Cryopreservation as Good as Fresh

Guardion™ freezes T-cells in under four minutes and maintains post-thaw quality comparable to fresh samples, delivering consistent viability across 24, 48, and 72 hours.

Every Component Built for Optimization of your Cryopreservation Process

Specifications

Dimensions

47 × 28 × 35 in (125 × 70 × 90 cm)
Weight

661 lbs (300 kg)

Freezer capacity
30L
Power requirements
220 V, 10 Amps
Temperature range
+15 °C to -45 °C
Cooling rate
1°C/min to 35°C/min
Standard freezing times
< 8 minutes
Capacity
Vials
300 x 2 mL vials
Bags
4 × 70 ml, 4 × 100 ml, 2 × 190 ml, 2 × 275 ml, 1 × 450 ml

Contactless racking system

Available for bags and vials
Custom bag and rack
Available as a service. Vitrafy can customize both packaging and racking solutions to fit your desired configuration.
Compliance & Regulatory
Quality and regulatory
Class 2 medical device (510(k) exempt and research use)
Manufactured under
ISO13485
FDA registration (Upcoming)
1H 2026 for sperm, OVA, blood platelets, red blood cells

Resources & Insights

Experience Guardion Firsthand

Visit our Southern California demo facility or schedule a remote demonstration with our team.

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